Indoles and derivatives

Aromatic bicyclic organic compounds that consists of a benzene ring fused to a pyrrole ring with formula: C₈H₇N.

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2,251 – 2,265 of 5,984 results

2,251

Medchemexpress LLC 3-(2-Aminoethyl)indole | 61-54-1 | 25 MG

Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist and an endogenous ligand of the aryl hydrocarbon receptor (AHR). It promotes intestinal anion secretion and fluid transport, accelerating gastrointestinal motility. Tryptamine also regulates Th17/Treg balance to inhibit neuroinflammation and participates in temperature regulation as a neuromodulator. It is used to study intestinal disorders and has shown efficacy in multiple sclerosis models.

Selective 5-HT4 receptor agonist and AHR ligand
Promotes intestinal anion secretion and fluid transport
Accelerates gastrointestinal motility
Regulates Th17/Treg balance to inhibit neuroinflammation
Participates in temperature regulation and spinal reflex regulation
Used to study intestinal disorders
Shown efficacy in multiple sclerosis models

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2,252

Medchemexpress LLC SARS-CoV-2-IN-7 | 2570461-66-2 | 98.8% | C14H8F3NOSe | 100 MG

SARS-CoV-2-IN-7 is an inhibitor that effectively inhibits viral replication with an IC50 of 844 nM in SARS-CoV-2-infected Vero E6 cells. It is intended for research use only and not sold to patients. The compound has a molecular weight of 342.17 and appears as a light yellow to orange solid.

Inhibits SARS-CoV-2 viral replication in Vero E6 cells (IC50 of 844 nM).
Exhibits cytotoxicity against human HaCaT cells (IC50 > 32 μM).
Highly soluble in DMSO (250 mg/mL) and forms clear solution with 10% DMSO and 90% corn oil (≥ 2.08 mg/mL) for in vivo experiments.
Powder storage: -20°C for 3 years or 4°C for 2 years.
In-solvent storage: -80°C for 6 months or -20°C for 1 month.
Light yellow to orange solid.

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2,253

Medchemexpress LLC Agrimol B | 55576-66-4 | 682.75 | 5 MG

Agrimol B is a polyphenol that acts as an orally active and potent SIRT1 activator. It demonstrates anti-adipogenic, anticancer, and antibacterial activity against plant pathogens. It significantly inhibits 3T3-L1 adipocyte differentiation by reducing the expression of PPARγ, C/EBPα, FAS, UCP-1, and apoE. Its effect on cancer cells is believed to stem from its influence on c-MYC, SKP2, and p27.